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Colin J Meyer Selected Research

bardoxolone methyl

1/2021Study Design and Baseline Characteristics of the CARDINAL Trial: A Phase 3 Study of Bardoxolone Methyl in Patients with Alport Syndrome.
1/2021Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD.
11/2019Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function.
10/2019Effect of bardoxolone methyl on the urine albumin-to-creatinine ratio in patients with type 2 diabetes and stage 4 chronic kidney disease.
1/2019Effects of Bardoxolone Methyl on QT Interval in Healthy Volunteers.
1/2019Effects of Bardoxolone Methyl on Magnesium in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease.
12/2018Effects of bardoxolone methyl on body weight, waist circumference and glycemic control in obese patients with type 2 diabetes mellitus and stage 4 chronic kidney disease.
1/2018Bardoxolone Methyl Improves Kidney Function in Patients with Chronic Kidney Disease Stage 4 and Type 2 Diabetes: Post-Hoc Analyses from Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes Study.
12/2014Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
1/2014Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
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Colin J Meyer Research Topics

Disease

16Chronic Renal Insufficiency
01/2021 - 01/2011
14Type 2 Diabetes Mellitus (MODY)
01/2021 - 01/2011
11Inflammation (Inflammations)
01/2021 - 01/2011
7Heart Failure
10/2019 - 01/2012
6Neoplasms (Cancer)
11/2019 - 06/2012
4Chronic Kidney Failure (Chronic Renal Failure)
01/2018 - 11/2013
2Friedreich Ataxia (Friedreich's Ataxia)
01/2021 - 01/2019
2Hypoxia (Hypoxemia)
12/2020 - 01/2016
2Albuminuria
10/2019 - 10/2012
2Body Weight (Weight, Body)
12/2018 - 12/2013
2Anemia
01/2017 - 11/2013
2Fibrosis (Cirrhosis)
06/2014 - 01/2012
1Hereditary Nephritis (Alport Syndrome)
01/2021
1Fatigue
01/2021
1Headache (Headaches)
01/2021
1Nausea
01/2021
1Diabetic Nephropathies (Diabetic Nephropathy)
11/2019
1Proteinuria
11/2019
1Nephrosis
11/2019
1Glomerulonephritis
11/2019
1Weight Loss (Weight Reduction)
12/2018
1Melanoma (Melanoma, Malignant)
01/2017
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017
1Retinopathy of Prematurity (Retrolental Fibroplasia)
01/2016
1Diabetic Retinopathy (Retinopathy, Diabetic)
01/2016
1Gliosis
01/2016
1Hyperoxia
01/2016
1Lung Neoplasms (Lung Cancer)
08/2015
1Breast Neoplasms (Breast Cancer)
08/2015
1Skin Diseases (Skin Disease)
07/2014
1Dermatitis
05/2014
1Necrosis
05/2014
1Radiodermatitis
05/2014
1Skin Ulcer
05/2014
1Erythema
05/2014
1Liver Diseases (Liver Disease)
07/2013
1Lymphoma (Lymphomas)
06/2012
1Cardiomegaly (Heart Hypertrophy)
01/2012
1Heart Diseases (Heart Disease)
01/2012
1Spasm (Spasms)
07/2011
1Insulin Resistance
02/2011
1Vascular System Injuries
01/2011

Drug/Important Bio-Agent (IBA)

19bardoxolone methylIBA
01/2021 - 01/2011
9TriterpenesIBA
01/2017 - 06/2012
5omaveloxoloneIBA
01/2021 - 05/2014
5AntioxidantsIBA
12/2020 - 07/2011
4AlbuminsIBA
01/2021 - 10/2012
4CreatinineIBA
01/2021 - 12/2013
4Transcription Factors (Transcription Factor)IBA
06/2014 - 02/2011
3bardoxoloneIBA
06/2014 - 01/2011
2Proteins (Proteins, Gene)FDA Link
12/2020 - 10/2012
2Pharmaceutical PreparationsIBA
01/2017 - 12/2014
2NF-kappa B (NF-kB)IBA
06/2014 - 05/2014
2oleananeIBA
01/2014 - 07/2013
2NF-E2-Related Factor 2IBA
01/2012 - 02/2011
1Alanine Transaminase (SGPT)IBA
01/2021
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021
1EnzymesIBA
01/2021
1TransferasesIBA
01/2021
1dh404 compoundIBA
11/2019
1MagnesiumIBA
01/2019
1InulinFDA Link
01/2018
1Alkaline PhosphataseIBA
01/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016
1Oxygen (Dioxygen)IBA
01/2016
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
08/2015
1Paclitaxel (Taxol)FDA LinkGeneric
08/2015
1Taxoids (Taxanes)IBA
08/2015
1peloruside AIBA
08/2015
1Docetaxel (Taxotere)FDA Link
08/2015
1Doxorubicin (Adriamycin)FDA LinkGeneric
08/2015
1Brain Natriuretic Peptide (Natrecor)FDA Link
12/2014
1Transforming Growth Factors (Transforming Growth Factor)IBA
06/2014
1NADPH Oxidases (NAD(P)H oxidase)IBA
06/2014
1Free RadicalsIBA
05/2014
1CollagenIBA
05/2014
1Endothelin Receptor AntagonistsIBA
01/2014
1Endothelins (Endothelin)IBA
01/2014
1Biomarkers (Surrogate Marker)IBA
11/2013
1Low Density Lipoprotein Receptor-Related Protein-2IBA
10/2012
1LipidsIBA
10/2012
1Phosphotransferases (Kinase)IBA
06/2012
1Cyclin D1IBA
06/2012
1Messenger RNA (mRNA)IBA
06/2012
18-Hydroxy-2'-DeoxyguanosineIBA
01/2012
14-hydroxy-2-nonenal (4-hydroxynonenal)IBA
01/2012
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
02/2011
1Insulin (Novolin)FDA Link
02/2011
1U 0126 (UO 126)IBA
02/2011
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
02/2011
1Glucose (Dextrose)FDA LinkGeneric
02/2011
1Phosphatidylinositols (Phosphatidylinositol)IBA
02/2011

Therapy/Procedure

2Radiotherapy
07/2014 - 05/2014
2Therapeutics
05/2014 - 01/2013
1Glycemic Control
12/2018
1Kidney Transplantation
01/2018
1Nephrectomy
01/2013